Review



mouse anti human mmp12  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 92

    Structured Review

    R&D Systems mouse anti human mmp12
    List of DEGs when the IgG4-ROD tissue was compared to all control tissues.
    Mouse Anti Human Mmp12, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 14 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti+human+mmp12/Human+MMP-12+Catalytic+Domain+Antibody/pmc07693346-287-2-7
    Average 92 stars, based on 14 article reviews
    mouse anti human mmp12 - by Bioz Stars, 2026-09
    92/100 stars

    Images

    1) Product Images from "Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing"

    Article Title: Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing

    Journal: Journal of Clinical Medicine

    doi: 10.3390/jcm9113458

    List of DEGs when the IgG4-ROD tissue was compared to all control tissues.
    Figure Legend Snippet: List of DEGs when the IgG4-ROD tissue was compared to all control tissues.

    Techniques Used: Control

    Differentially expressed genes of IgG4-ROD versus orbital MALT lymphoma: top 40 in descending p value.
    Figure Legend Snippet: Differentially expressed genes of IgG4-ROD versus orbital MALT lymphoma: top 40 in descending p value.

    Techniques Used:

    Differentially expressed genes of IgG4-ROD versus RLH: top 40 in descending p value.
    Figure Legend Snippet: Differentially expressed genes of IgG4-ROD versus RLH: top 40 in descending p value.

    Techniques Used:

    Results of real-time PCR for validation of differentially expressed genes obtained from RNA sequencing. *** Messenger RNA of MMP12 and SPP1 in immunoglobulin G4-related ophthalmic disease is significantly higher than mucosa-associated lymphoid tissue lymphoma ( p = 2.7141 × 10 −8 and 1.2044 × 10 −7 , respectively). Statistical analysis was performed by a Mann–Whitney U test ( n = 30). IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.
    Figure Legend Snippet: Results of real-time PCR for validation of differentially expressed genes obtained from RNA sequencing. *** Messenger RNA of MMP12 and SPP1 in immunoglobulin G4-related ophthalmic disease is significantly higher than mucosa-associated lymphoid tissue lymphoma ( p = 2.7141 × 10 −8 and 1.2044 × 10 −7 , respectively). Statistical analysis was performed by a Mann–Whitney U test ( n = 30). IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.

    Techniques Used: Real-time Polymerase Chain Reaction, Biomarker Discovery, RNA Sequencing, MANN-WHITNEY

    Representative immunohistochemical staining patterns of formalin-fixed, paraffin-embedded sections (MMP12: magnification 400×, bar: 50 μm, SPP1: magnification 200×, bar: 100μm). The upper row is immunoreactivity of MMP12, and the lower row is immunoreactivity of SPP1. From left column to right column, IgG4-ROD, MALT lymphoma, RLH, and the lacrimal gland tissue section are shown. Many MMP12 positive cells are observable in the fibrotic areas and follicular areas of IgG4-ROD tissues. SPP1 is intensely stained in the fibrotic part of IgG4-ROD. IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, RLH: Reactive lymphoid hyperplasia, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.
    Figure Legend Snippet: Representative immunohistochemical staining patterns of formalin-fixed, paraffin-embedded sections (MMP12: magnification 400×, bar: 50 μm, SPP1: magnification 200×, bar: 100μm). The upper row is immunoreactivity of MMP12, and the lower row is immunoreactivity of SPP1. From left column to right column, IgG4-ROD, MALT lymphoma, RLH, and the lacrimal gland tissue section are shown. Many MMP12 positive cells are observable in the fibrotic areas and follicular areas of IgG4-ROD tissues. SPP1 is intensely stained in the fibrotic part of IgG4-ROD. IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, RLH: Reactive lymphoid hyperplasia, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.

    Techniques Used: Immunohistochemical staining, Staining, Formalin-fixed Paraffin-Embedded

    Related Articles

    Immunostaining:

    Article Title: Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing
    Article Snippet: .. Immunostaining by mouse anti-human MMP12 (1:50, MAB919, R&D Systems, Minneapolis, MN, USA) and rabbit anti-human SPP1 (1:1000, HPA027541, Atlas Antibodies, Bromma, Sweden) was performed using paraffin-embedded biopsy tissues. ..



    Similar Products

    92
    R&D Systems mouse anti human mmp12
    List of DEGs when the IgG4-ROD tissue was compared to all control tissues.
    Mouse Anti Human Mmp12, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti+human+mmp12/Human+MMP-12+Catalytic+Domain+Antibody/pmc07693346-287-2-7
    Average 92 stars, based on 1 article reviews
    mouse anti human mmp12 - by Bioz Stars, 2026-09
    92/100 stars
      Buy from Supplier

    Image Search Results


    List of DEGs when the IgG4-ROD tissue was compared to all control tissues.

    Journal: Journal of Clinical Medicine

    Article Title: Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing

    doi: 10.3390/jcm9113458

    Figure Lengend Snippet: List of DEGs when the IgG4-ROD tissue was compared to all control tissues.

    Article Snippet: Immunostaining by mouse anti-human MMP12 (1:50, MAB919, R&D Systems, Minneapolis, MN, USA) and rabbit anti-human SPP1 (1:1000, HPA027541, Atlas Antibodies, Bromma, Sweden) was performed using paraffin-embedded biopsy tissues.

    Techniques: Control

    Differentially expressed genes of IgG4-ROD versus orbital MALT lymphoma: top 40 in descending p value.

    Journal: Journal of Clinical Medicine

    Article Title: Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing

    doi: 10.3390/jcm9113458

    Figure Lengend Snippet: Differentially expressed genes of IgG4-ROD versus orbital MALT lymphoma: top 40 in descending p value.

    Article Snippet: Immunostaining by mouse anti-human MMP12 (1:50, MAB919, R&D Systems, Minneapolis, MN, USA) and rabbit anti-human SPP1 (1:1000, HPA027541, Atlas Antibodies, Bromma, Sweden) was performed using paraffin-embedded biopsy tissues.

    Techniques:

    Differentially expressed genes of IgG4-ROD versus RLH: top 40 in descending p value.

    Journal: Journal of Clinical Medicine

    Article Title: Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing

    doi: 10.3390/jcm9113458

    Figure Lengend Snippet: Differentially expressed genes of IgG4-ROD versus RLH: top 40 in descending p value.

    Article Snippet: Immunostaining by mouse anti-human MMP12 (1:50, MAB919, R&D Systems, Minneapolis, MN, USA) and rabbit anti-human SPP1 (1:1000, HPA027541, Atlas Antibodies, Bromma, Sweden) was performed using paraffin-embedded biopsy tissues.

    Techniques:

    Results of real-time PCR for validation of differentially expressed genes obtained from RNA sequencing. *** Messenger RNA of MMP12 and SPP1 in immunoglobulin G4-related ophthalmic disease is significantly higher than mucosa-associated lymphoid tissue lymphoma ( p = 2.7141 × 10 −8 and 1.2044 × 10 −7 , respectively). Statistical analysis was performed by a Mann–Whitney U test ( n = 30). IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.

    Journal: Journal of Clinical Medicine

    Article Title: Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing

    doi: 10.3390/jcm9113458

    Figure Lengend Snippet: Results of real-time PCR for validation of differentially expressed genes obtained from RNA sequencing. *** Messenger RNA of MMP12 and SPP1 in immunoglobulin G4-related ophthalmic disease is significantly higher than mucosa-associated lymphoid tissue lymphoma ( p = 2.7141 × 10 −8 and 1.2044 × 10 −7 , respectively). Statistical analysis was performed by a Mann–Whitney U test ( n = 30). IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.

    Article Snippet: Immunostaining by mouse anti-human MMP12 (1:50, MAB919, R&D Systems, Minneapolis, MN, USA) and rabbit anti-human SPP1 (1:1000, HPA027541, Atlas Antibodies, Bromma, Sweden) was performed using paraffin-embedded biopsy tissues.

    Techniques: Real-time Polymerase Chain Reaction, Biomarker Discovery, RNA Sequencing, MANN-WHITNEY

    Representative immunohistochemical staining patterns of formalin-fixed, paraffin-embedded sections (MMP12: magnification 400×, bar: 50 μm, SPP1: magnification 200×, bar: 100μm). The upper row is immunoreactivity of MMP12, and the lower row is immunoreactivity of SPP1. From left column to right column, IgG4-ROD, MALT lymphoma, RLH, and the lacrimal gland tissue section are shown. Many MMP12 positive cells are observable in the fibrotic areas and follicular areas of IgG4-ROD tissues. SPP1 is intensely stained in the fibrotic part of IgG4-ROD. IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, RLH: Reactive lymphoid hyperplasia, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.

    Journal: Journal of Clinical Medicine

    Article Title: Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing

    doi: 10.3390/jcm9113458

    Figure Lengend Snippet: Representative immunohistochemical staining patterns of formalin-fixed, paraffin-embedded sections (MMP12: magnification 400×, bar: 50 μm, SPP1: magnification 200×, bar: 100μm). The upper row is immunoreactivity of MMP12, and the lower row is immunoreactivity of SPP1. From left column to right column, IgG4-ROD, MALT lymphoma, RLH, and the lacrimal gland tissue section are shown. Many MMP12 positive cells are observable in the fibrotic areas and follicular areas of IgG4-ROD tissues. SPP1 is intensely stained in the fibrotic part of IgG4-ROD. IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, RLH: Reactive lymphoid hyperplasia, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.

    Article Snippet: Immunostaining by mouse anti-human MMP12 (1:50, MAB919, R&D Systems, Minneapolis, MN, USA) and rabbit anti-human SPP1 (1:1000, HPA027541, Atlas Antibodies, Bromma, Sweden) was performed using paraffin-embedded biopsy tissues.

    Techniques: Immunohistochemical staining, Staining, Formalin-fixed Paraffin-Embedded