mouse anti human mmp12 (R&D Systems)
Structured Review

Mouse Anti Human Mmp12, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 14 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+anti+human+mmp12/Human+MMP-12+Catalytic+Domain+Antibody/pmc07693346-287-2-7
Average 92 stars, based on 14 article reviews
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1) Product Images from "Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing"
Article Title: Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing
Journal: Journal of Clinical Medicine
doi: 10.3390/jcm9113458
Figure Legend Snippet: List of DEGs when the IgG4-ROD tissue was compared to all control tissues.
Techniques Used: Control
Figure Legend Snippet: Differentially expressed genes of IgG4-ROD versus orbital MALT lymphoma: top 40 in descending p value.
Techniques Used:
Figure Legend Snippet: Differentially expressed genes of IgG4-ROD versus RLH: top 40 in descending p value.
Techniques Used:
Figure Legend Snippet: Results of real-time PCR for validation of differentially expressed genes obtained from RNA sequencing. *** Messenger RNA of MMP12 and SPP1 in immunoglobulin G4-related ophthalmic disease is significantly higher than mucosa-associated lymphoid tissue lymphoma ( p = 2.7141 × 10 −8 and 1.2044 × 10 −7 , respectively). Statistical analysis was performed by a Mann–Whitney U test ( n = 30). IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.
Techniques Used: Real-time Polymerase Chain Reaction, Biomarker Discovery, RNA Sequencing, MANN-WHITNEY
Figure Legend Snippet: Representative immunohistochemical staining patterns of formalin-fixed, paraffin-embedded sections (MMP12: magnification 400×, bar: 50 μm, SPP1: magnification 200×, bar: 100μm). The upper row is immunoreactivity of MMP12, and the lower row is immunoreactivity of SPP1. From left column to right column, IgG4-ROD, MALT lymphoma, RLH, and the lacrimal gland tissue section are shown. Many MMP12 positive cells are observable in the fibrotic areas and follicular areas of IgG4-ROD tissues. SPP1 is intensely stained in the fibrotic part of IgG4-ROD. IgG4-ROD: Immunoglobulin G4 related ophthalmic disease, MALT: Mucosa-associated lymph tissue, RLH: Reactive lymphoid hyperplasia, MMP12: Matrix metallopeptidase 12, SPP1: Secreted phosphoprotein 1.
Techniques Used: Immunohistochemical staining, Staining, Formalin-fixed Paraffin-Embedded
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